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Rapamycin prevents endothelial cell migration by inhibiting the endothelial-to-mesenchymal transition and matrix metalloproteinase-2 and -9: An in vitro study

PURPOSE: To evaluate the influence of rapamycin on endothelial-mesenchymal transition and matrix metalloproteinase (MMP) secretion by human umbilical vein endothelial cell line EA.hy926 and explore rapamycin’s angiogenesis inhibition mechanism. METHODS: EA.hy926 cells were cultivated in vitro. After...

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Detalhes bibliográficos
Main Authors: Gao, Hua, Zhang, Jingjing, Liu, Ting, Shi, Weiyun
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247170/
https://ncbi.nlm.nih.gov/pubmed/22219636
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