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A robust penalized method for the analysis of noisy DNA copy number data

BACKGROUND: Deletions and amplifications of the human genomic DNA copy number are the causes of numerous diseases, such as, various forms of cancer. Therefore, the detection of DNA copy number variations (CNV) is important in understanding the genetic basis of many diseases. Various techniques and p...

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Bibliographic Details
Main Authors: Gao, Xiaoli, Huang, Jian
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247090/
https://ncbi.nlm.nih.gov/pubmed/20868505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-517
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