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Reconstituted synaptotagmin I mediates vesicle docking, priming, and fusion

The synaptic vesicle protein synaptotagmin I (syt) promotes exocytosis via its ability to penetrate membranes in response to binding Ca(2+) and through direct interactions with SNARE proteins. However, studies using full-length (FL) membrane-embedded syt in reconstituted fusion assays have yielded c...

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Détails bibliographiques
Auteurs principaux: Wang, Zhao, Liu, Huisheng, Gu, Yiwen, Chapman, Edwin R.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246889/
https://ncbi.nlm.nih.gov/pubmed/22184197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201104079
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