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A Sibling-augmented Case-only Approach for Assessing Multiplicative Gene-Environment Interactions

Family-based designs protect analyses of genetic effects from bias that is due to population stratification. Investigators have assumed that this robustness extends to assessments of gene-environment interaction. Unfortunately, this assumption fails for the common scenario in which the genotyped var...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Weinberg, Clarice R., Shi, Min, Umbach, David M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246688/
https://ncbi.nlm.nih.gov/pubmed/22021562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwr231
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