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Family-based Gene-by-Environment Interaction Studies: Revelations and Remedies

Bias can arise in case-control studies of genotype effects if the underlying population is structured (genetically stratified or admixed). Nuclear-family-based studies enjoy robustness against such bias, provided that inference conditions properly on the parents. Investigators have extended family-b...

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Detalhes bibliográficos
Main Authors: Shi, Min, Umbach, David M., Weinberg, Clarice R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132804/
https://ncbi.nlm.nih.gov/pubmed/21490534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/EDE.0b013e318212fec6
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