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Using Cases and Parents to Study Multiplicative Gene-by-Environment Interaction

With case-parent triads, one can estimate genotype relative risks by measuring the apparent overtransmission of susceptibility genotypes from parents to affected offspring. Results obtained using such designs, properly analyzed, resist both bias due to population structure and bias due to self-selec...

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Detalhes bibliográficos
Main Authors: Kistner, Emily O., Shi, Min, Weinberg, Clarice R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733309/
https://ncbi.nlm.nih.gov/pubmed/19483188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwp118
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