Antibodies against the cardiac sodium/bicarbonate co-transporter (NBCe1) as pharmacological tools

BACKGROUND AND PURPOSE: Na(+)/HCO(3)(-) co-transport (NBC) regulates intracellular pH (pH(i)) in the heart. We have studied the electrogenic NBC isoform NBCe1 by examining the effect of functional antibodies to this protein. EXPERIMENTAL APPROACH: We generated two antibodies against putative extrace...

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Detalhes bibliográficos
Main Authors: De Giusti, Verónica C, Orlowski, Alejandro, Villa-Abrille, María C, de Cingolani, Gladys E Chiappe, Casey, Joseph R, Alvarez, Bernardo V, Aiello, Ernesto A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2011
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246661/
https://ncbi.nlm.nih.gov/pubmed/21595652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01496.x
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