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The cardiac electrogenic sodium/bicarbonate cotransporter (NBCe1) is activated by aldosterone through the G protein-coupled receptor 30 (GPR 30)

The sodium/bicarbonate cotransporter (NBC) transports extracellular Na(+) and HCO(3)(−) into the cytoplasm upon intracellular acidosis, restoring the acidic pH(i) to near neutral values. Two different NBC isoforms have been described in the heart, the electroneutral NBCn1 (1Na(+):1HCO(3)(−)) and the...

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Detalhes bibliográficos
Publicado no:Channels (Austin)
Main Authors: Orlowski, Alejandro, De Giusti, Verónica C., Ciancio, María C., Espejo, María S., Aiello, Ernesto A.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988451/
https://ncbi.nlm.nih.gov/pubmed/27249584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2016.1195533
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