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The cardiac electrogenic sodium/bicarbonate cotransporter (NBCe1) is activated by aldosterone through the G protein-coupled receptor 30 (GPR 30)
The sodium/bicarbonate cotransporter (NBC) transports extracellular Na(+) and HCO(3)(−) into the cytoplasm upon intracellular acidosis, restoring the acidic pH(i) to near neutral values. Two different NBC isoforms have been described in the heart, the electroneutral NBCn1 (1Na(+):1HCO(3)(−)) and the...
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Publicado no: | Channels (Austin) |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4988451/ https://ncbi.nlm.nih.gov/pubmed/27249584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2016.1195533 |
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