Systemic urocortin 2, but not urocortin 1 or stressin(1)-A, suppresses feeding via CRF(2) receptors without malaise and stress

BACKGROUND AND PURPOSE: Infusion of corticotropin-releasing factor (CRF)/urocortin (Ucn) family peptides suppresses feeding in mice. We examined whether rats show peripheral CRF/Ucn-induced anorexia and determined its behavioural and pharmacological bases. EXPERIMENTAL APPROACH: Male Wistar rats (n...

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Detalhes bibliográficos
Main Authors: Fekete, ÉM, Zhao, Y, Szücs, A, Sabino, V, Cottone, P, Rivier, J, Vale, WW, Koob, GF, Zorrilla, EP
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2011
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246660/
https://ncbi.nlm.nih.gov/pubmed/21627635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01512.x
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