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Whole-genome sequencing of rifampicin-resistant M. tuberculosis strains identifies compensatory mutations in RNA polymerase
Drug-resistant bacteria are emerging worldwide, despite frequently being less fit than drug-susceptible strains(1). Data from model systems suggest the fitness cost of antimicrobial resistance can be mitigated by compensatory mutations(2). However, current evidence that compensatory evolution plays...
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| Main Authors: | , , , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2011
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3246538/ https://ncbi.nlm.nih.gov/pubmed/22179134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.1038 |
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