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Genotyping of Genetically Monomorphic Bacteria: DNA Sequencing in Mycobacterium tuberculosis Highlights the Limitations of Current Methodologies

Because genetically monomorphic bacterial pathogens harbour little DNA sequence diversity, most current genotyping techniques used to study the epidemiology of these organisms are based on mobile or repetitive genetic elements. Molecular markers commonly used in these bacteria include Clustered Regu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Comas, Iñaki, Homolka, Susanne, Niemann, Stefan, Gagneux, Sebastien
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772813/
https://ncbi.nlm.nih.gov/pubmed/19915672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007815
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