Genotyping of Genetically Monomorphic Bacteria: DNA Sequencing in Mycobacterium tuberculosis Highlights the Limitations of Current Methodologies

Because genetically monomorphic bacterial pathogens harbour little DNA sequence diversity, most current genotyping techniques used to study the epidemiology of these organisms are based on mobile or repetitive genetic elements. Molecular markers commonly used in these bacteria include Clustered Regu...

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Autors principals: Comas, Iñaki, Homolka, Susanne, Niemann, Stefan, Gagneux, Sebastien
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772813/
https://ncbi.nlm.nih.gov/pubmed/19915672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007815
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