Genotyping of Genetically Monomorphic Bacteria: DNA Sequencing in Mycobacterium tuberculosis Highlights the Limitations of Current Methodologies

Because genetically monomorphic bacterial pathogens harbour little DNA sequence diversity, most current genotyping techniques used to study the epidemiology of these organisms are based on mobile or repetitive genetic elements. Molecular markers commonly used in these bacteria include Clustered Regu...

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Библиографические подробности
Главные авторы: Comas, Iñaki, Homolka, Susanne, Niemann, Stefan, Gagneux, Sebastien
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2009
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772813/
https://ncbi.nlm.nih.gov/pubmed/19915672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007815
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