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Genotyping of Genetically Monomorphic Bacteria: DNA Sequencing in Mycobacterium tuberculosis Highlights the Limitations of Current Methodologies

Because genetically monomorphic bacterial pathogens harbour little DNA sequence diversity, most current genotyping techniques used to study the epidemiology of these organisms are based on mobile or repetitive genetic elements. Molecular markers commonly used in these bacteria include Clustered Regu...

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Bibliografiske detaljer
Main Authors: Comas, Iñaki, Homolka, Susanne, Niemann, Stefan, Gagneux, Sebastien
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772813/
https://ncbi.nlm.nih.gov/pubmed/19915672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007815
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