The Inducible Deletion of Drosha and MicroRNAs In Mature Podocytes Results In A Collapsing Glomerulopathy

MiRNAs have been shown to play key roles in both the function and differentiation of a number of different cell types. Drosha and Dicer, two RNAase III enzymes, function in a stepwise manner to generate a mature miRNA. Previous studies have demonstrated that podocyte-specific deletion of Dicer durin...

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Detalhes bibliográficos
Main Authors: Zhdanova, Olga, Srivastava, Shekhar, Di, Lie, Li, Zhai, Tchelebi, Leila, Dworkin, Sara, Johnstone, Duncan B, Zavadil, Jiri, Chong, Mark M., Littman, Dan R., Holzman, Lawrence B., Barisoni, Laura, Skolnik, Edward Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246347/
https://ncbi.nlm.nih.gov/pubmed/21544061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2011.122
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