Changes in exon–intron structure during vertebrate evolution affect the splicing pattern of exons

Exon–intron architecture is one of the major features directing the splicing machinery to the short exons that are located within long flanking introns. However, the evolutionary dynamics of exon–intron architecture and its impact on splicing is largely unknown. Using a comparative genomic approach,...

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Detalhes bibliográficos
Main Authors: Gelfman, Sahar, Burstein, David, Penn, Osnat, Savchenko, Anna, Amit, Maayan, Schwartz, Schraga, Pupko, Tal, Ast, Gil
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246205/
https://ncbi.nlm.nih.gov/pubmed/21974994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.119834.110
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