Changes in exon–intron structure during vertebrate evolution affect the splicing pattern of exons

Exon–intron architecture is one of the major features directing the splicing machinery to the short exons that are located within long flanking introns. However, the evolutionary dynamics of exon–intron architecture and its impact on splicing is largely unknown. Using a comparative genomic approach,...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Gelfman, Sahar, Burstein, David, Penn, Osnat, Savchenko, Anna, Amit, Maayan, Schwartz, Schraga, Pupko, Tal, Ast, Gil
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2012
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246205/
https://ncbi.nlm.nih.gov/pubmed/21974994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.119834.110
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