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Optimized detection of transcription factor-binding sites in ChIP-seq experiments
We developed a computational procedure for optimizing the binding site detections in a given ChIP-seq experiment by maximizing their reproducibility under bootstrap sampling. We demonstrate how the procedure can improve the detection accuracies beyond those obtained with the default settings of popu...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3245948/ https://ncbi.nlm.nih.gov/pubmed/22009681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr839 |
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