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DNA-induced dimerization of the single-stranded DNA binding telomeric protein Pot1 from Schizosaccharomyces pombe

Eukaryotic chromosome ends are protected from illicit DNA joining by protein–DNA complexes called telomeres. In most studied organisms, telomeric DNA is composed of multiple short G-rich repeats that end in a single-stranded tail that is protected by the protein POT1. Mammalian POT1 binds two telome...

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Detalhes bibliográficos
Main Authors: Nandakumar, Jayakrishnan, Cech, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245936/
https://ncbi.nlm.nih.gov/pubmed/21911358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr721
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