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DNA-induced dimerization of the single-stranded DNA binding telomeric protein Pot1 from Schizosaccharomyces pombe

Eukaryotic chromosome ends are protected from illicit DNA joining by protein–DNA complexes called telomeres. In most studied organisms, telomeric DNA is composed of multiple short G-rich repeats that end in a single-stranded tail that is protected by the protein POT1. Mammalian POT1 binds two telome...

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Autori principali: Nandakumar, Jayakrishnan, Cech, Thomas R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245936/
https://ncbi.nlm.nih.gov/pubmed/21911358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr721
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