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Integrated genome-wide analysis of transcription factor occupancy, RNA polymerase II binding and steady-state RNA levels identify differentially regulated functional gene classes

Routine methods for assaying steady-state mRNA levels such as RNA-seq and micro-arrays are commonly used as readouts to study the role of transcription factors (TFs) in gene expression regulation. However, cellular RNA levels do not solely depend on activity of TFs and subsequent transcription by RN...

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Detalhes bibliográficos
Main Authors: Mokry, Michal, Hatzis, Pantelis, Schuijers, Jurian, Lansu, Nico, Ruzius, Frans-Paul, Clevers, Hans, Cuppen, Edwin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245935/
https://ncbi.nlm.nih.gov/pubmed/21914722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr720
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