Genome-wide co-localization of active EGFR and downstream ERK pathway kinases mirrors mitogen-inducible RNA polymerase 2 genomic occupancy

Genome-wide mechanisms that coordinate expression of subsets of functionally related genes are largely unknown. Recent studies show that receptor tyrosine kinases and components of signal transduction cascades including the extracellular signal-regulated protein kinase (ERK), once thought to act pre...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Mikula, M., Skrzypczak, M., Goryca, K., Paczkowska, K., Ledwon, J.K., Statkiewicz, M., Kulecka, M., Grzelak, M., Dabrowska, M., Kuklinska, U., Karczmarski, J., Rumienczyk, I., Jastrzebski, K., Miaczynska, M., Ginalski, K., Bomsztyk, K., Ostrowski, J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
Soggetti:
Gene regulation, Chromatin and Epigenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137434/
https://ncbi.nlm.nih.gov/pubmed/27587583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw763
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