Exome scale map of genetic alterations promoting metastasis in colorectal cancer

Abstract Background Approximately 90% of colorectal cancer (CRC) deaths are caused by tumors ability to migrate into the adjacent tissues and metastase into distant organs. More than 40 genes have been causally linked to the development of CRC but no mutations have been associated with metastasis ye...

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Autors principals: Krzysztof Goryca, Maria Kulecka, Agnieszka Paziewska, Michalina Dabrowska, Marta Grzelak, Magdalena Skrzypczak, Krzysztof Ginalski, Andrzej Mroz, Andrzej Rutkowski, Katarzyna Paczkowska, Michal Mikula, Jerzy Ostrowski
Format: Artigo
Idioma:Inglês
Publicat: BMC 2018-09-01
Col·lecció:BMC Genetics
Matèries:
Colorectal cancer
Metastasis
Exome
Gene expression
Sequencing
Accés en línia:http://link.springer.com/article/10.1186/s12863-018-0673-0
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