Inhibition of p53 acetylation by INHAT subunit SET/TAF-Iβ represses p53 activity

The tumor suppressor p53 responds to a wide variety of cellular stress signals. Among potential regulatory pathways, post-translational modifications such as acetylation by CBP/p300 and PCAF have been suggested for modulation of p53 activity. However, exactly how p53 acetylation is modulated remains...

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Bibliographic Details
Main Authors: Kim, Ji-Young, Lee, Kyu-Sun, Seol, Jin-Ee, Yu, Kweon, Chakravarti, Debabrata, Seo, Sang-Beom
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Gene Regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245910/
https://ncbi.nlm.nih.gov/pubmed/21911363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr614
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