DREAM and RB cooperate to induce gene repression and cell-cycle arrest in response to p53 activation

Most human cancers acquire mutations causing defects in the p53 signaling pathway. The tumor suppressor p53 becomes activated in response to genotoxic stress and is essential for arresting the cell cycle to facilitate DNA repair or to initiate apoptosis. p53-induced cell cycle-arrest is mediated by...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Uxa, Sigrid, Bernhart, Stephan H, Mages, Christina F S, Fischer, Martin, Kohler, Robin, Hoffmann, Steve, Stadler, Peter F, Engeland, Kurt, Müller, Gerd A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6753476/
https://ncbi.nlm.nih.gov/pubmed/31400114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz635
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados