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Human papilloma virus E7 oncoprotein abrogates the p53-p21-DREAM pathway
High risk human papilloma viruses cause several types of cancer. The HPV oncoproteins E6 and E7 are essential for oncogenic cell transformation. E6 mediates the degradation of the tumor suppressor p53, and E7 can form complexes with the retinoblastoma pRB tumor suppressor. Recently, it has been show...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5453983/ https://ncbi.nlm.nih.gov/pubmed/28572607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02831-9 |
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