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DNA damage bypass operates in the S and G2 phases of the cell cycle and exhibits differential mutagenicity
Translesion DNA synthesis (TLS) employs low-fidelity DNA polymerases to bypass replication-blocking lesions, and being associated with chromosomal replication was presumed to occur in the S phase of the cell cycle. Using immunostaining with anti-replication protein A antibodies, we show that in UV-i...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3245908/ https://ncbi.nlm.nih.gov/pubmed/21908406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr596 |
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