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Targeted enrichment of genomic DNA regions for next-generation sequencing

In this review, we discuss the latest targeted enrichment methods and aspects of their utilization along with second-generation sequencing for complex genome analysis. In doing so, we provide an overview of issues involved in detecting genetic variation, for which targeted enrichment has become a po...

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Detalles Bibliográficos
Main Authors: Mertes, Florian, ElSharawy, Abdou, Sauer, Sascha, van Helvoort, Joop M.L.M., van der Zaag, P.J., Franke, Andre, Nilsson, Mats, Lehrach, Hans, Brookes, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245553/
https://ncbi.nlm.nih.gov/pubmed/22121152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bfgp/elr033
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