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How do mutations in lamins A and C cause disease?
Mutations in lamins A and C, nuclear intermediate-filament proteins in nearly all somatic cells, cause a variety of diseases that primarily affect striated muscle, adipocytes, or peripheral nerves or cause features of premature aging. Two new studies use lamin A/C–deficient mice, which develop stria...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2004
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC324546/ https://ncbi.nlm.nih.gov/pubmed/14755330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420832 |
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