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Site and mechanism of leptin action in a rodent form of congenital lipodystrophy
Lipodystrophy is characterized by the complete or partial absence of adipose tissue, insulin resistance, hepatic steatosis, and leptin deficiency. Here, we show that low-dose central leptin corrects the insulin resistance and fatty liver of lipodystrophic aP2-nSREBP-1c mice, while the same dose give...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC324539/ https://ncbi.nlm.nih.gov/pubmed/14755338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419511 |
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