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Loss of stearoyl-CoA desaturase 1 rescues cardiac function in obese leptin-deficient mice
The heart of leptin-deficient ob/ob mice is characterized by pathologic left ventricular hypertrophy along with elevated triglyceride (TG) content, increased stearoyl-CoA desaturase (SCD) activity, and increased myocyte apoptosis. In the present study, using an ob/ob;SCD1(−/−) mouse model, we tested...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The American Society for Biochemistry and Molecular Biology
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903830/ https://ncbi.nlm.nih.gov/pubmed/20363835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M003780 |
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