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Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscle
We have shown previously that mice with a targeted disruption in the stearoyl-CoA desaturase 1 gene (SCD1(-/-)) have increased insulin sensitivity compared with control mice. Here we show that the SCD1(-/-) mice have increased insulin signaling in muscle. The basal tyrosine phosphorylation of the in...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC196935/ https://ncbi.nlm.nih.gov/pubmed/12960377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1934571100 |
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