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Joint Ancestry and Association Testing in Admixed Individuals

For samples of admixed individuals, it is possible to test for both ancestry effects via admixture mapping and genotype effects via association mapping. Here, we describe a joint test called BMIX that combines admixture and association statistics at single markers. We first perform high-density admi...

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Bibliographic Details
Main Authors: Shriner, Daniel, Adeyemo, Adebowale, Rotimi, Charles N.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245293/
https://ncbi.nlm.nih.gov/pubmed/22216000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002325
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