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Cell organization, growth, and neural and cardiac development require αII-spectrin

Spectrin α2 (αII-spectrin) is a scaffolding protein encoded by the Spna2 gene and constitutively expressed in most tissues. Exon trapping of Spna2 in C57BL/6 mice allowed targeted disruption of αII-spectrin. Heterozygous animals displayed no phenotype by 2 years of age. Homozygous deletion of Spna2...

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Main Authors: Stankewich, Michael C., Cianci, Carol D., Stabach, Paul R., Ji, Lan, Nath, Anjali, Morrow, Jon S.
格式: Artigo
語言:Inglês
出版: Company of Biologists 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244980/
https://ncbi.nlm.nih.gov/pubmed/22159418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.080374
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