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Accounting for Population Stratification in Practice: A Comparison of the Main Strategies Dedicated to Genome-Wide Association Studies

Genome-Wide Association Studies are powerful tools to detect genetic variants associated with diseases. Their results have, however, been questioned, in part because of the bias induced by population stratification. This is a consequence of systematic differences in allele frequencies due to the dif...

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Detalhes bibliográficos
Main Authors: Bouaziz, Matthieu, Ambroise, Christophe, Guedj, Mickael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244428/
https://ncbi.nlm.nih.gov/pubmed/22216125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028845
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