Accounting for multiple comparisons in a genome-wide association study (GWAS)

BACKGROUND: As we enter an era when testing millions of SNPs in a single gene association study will become the standard, consideration of multiple comparisons is an essential part of determining statistical significance. Bonferroni adjustments can be made but are conservative due to the preponderan...

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Détails bibliographiques
Auteurs principaux: Johnson, Randall C, Nelson, George W, Troyer, Jennifer L, Lautenberger, James A, Kessing, Bailey D, Winkler, Cheryl A, O'Brien, Stephen J
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023815/
https://ncbi.nlm.nih.gov/pubmed/21176216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-724
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