Accounting for multiple comparisons in a genome-wide association study (GWAS)

BACKGROUND: As we enter an era when testing millions of SNPs in a single gene association study will become the standard, consideration of multiple comparisons is an essential part of determining statistical significance. Bonferroni adjustments can be made but are conservative due to the preponderan...

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Bibliographische Detailangaben
Hauptverfasser: Johnson, Randall C, Nelson, George W, Troyer, Jennifer L, Lautenberger, James A, Kessing, Bailey D, Winkler, Cheryl A, O'Brien, Stephen J
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023815/
https://ncbi.nlm.nih.gov/pubmed/21176216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-724
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