Analysis of drug combinations: current methodological landscape

Por Foucquier, Julie, Guedj, Mickael
Publicado no Pharmacol Res Perspect (2015)

A two-step multiple-marker strategy for genome-wide association studies

Por Aschard, Hugues, Guedj, Mickaël, Demenais, Florence
Publicado em 2007

Accounting for Population Stratification in Practice: A Comparison of the Main Strategies Dedicated to Genome-Wide Association Studies

Por Bouaziz, Matthieu, Ambroise, Christophe, Guedj, Mickael
Publicado em 2011

Kerfdr: a semi-parametric kernel-based approach to local false discovery rate estimation

Por Guedj, Mickael, Robin, Stephane, Celisse, Alain, Nuel, Gregory
Publicado em 2009

SHIPS: Spectral Hierarchical Clustering for the Inference of Population Structure in Genetic Studies

Por Bouaziz, Matthieu, Paccard, Caroline, Guedj, Mickael, Ambroise, Christophe
Publicado em 2012

Should We Abandon the t-Test in the Analysis of Gene Expression Microarray Data: A Comparison of Variance Modeling Strategies

Por Jeanmougin, Marine, de Reynies, Aurelien, Marisa, Laetitia, Paccard, Caroline, Nuel, Gregory, Guedj, Mickael
Publicado em 2010

A Reliable Method for the Selection of Exploitable Melanoma Archival Paraffin Embedded Tissues for Transcript Biomarker Profiling

Por Lebbe, Celeste, Guedj, Mickael, Basset-Seguin, Nicole, Podgorniak, Marie Pierre, Menashi, Suzanne, Janin, Anne, Mourah, Samia
Publicado em 2012

A Multi-Marker Genetic Association Test Based on the Rasch Model Applied to Alzheimer’s Disease

Por Wang, Wenjia, Mandel, Jonas, Bouaziz, Jan, Commenges, Daniel, Nabirotchkine, Serguei, Chumakov, Ilya, Cohen, Daniel, Guedj, Mickaël
Publicado no PLoS One (2015)

A meta-analysis of randomized double-blind clinical trials in CMT1A to assess the change from baseline in CMTNS and ONLS scales after one year of treatment

Por Mandel, Jonas, Bertrand, Viviane, Lehert, Philippe, Attarian, Shahram, Magy, Laurent, Micallef, Joëlle, Chumakov, Ilya, Scart-Grès, Catherine, Guedj, Mickael, Cohen, Daniel
Publicado no Orphanet J Rare Dis (2015)

ChEBI: a database and ontology for chemical entities of biological interest

Por Degtyarenko, Kirill, de Matos, Paula, Ennis, Marcus, Hastings, Janna, Zbinden, Martin, McNaught, Alan, Alcántara, Rafael, Darsow, Michael, Guedj, Mickaël, Ashburner, Michael
Publicado em 2008

Combination of acamprosate and baclofen as a promising therapeutic approach for Parkinson’s disease

Por Hajj, Rodolphe, Milet, Aude, Toulorge, Damien, Cholet, Nathalie, Laffaire, Julien, Foucquier, Julie, Robelet, Sandra, Mitry, Richard, Guedj, Mickael, Nabirotchkin, Serguei, Chumakov, Ilya, Cohen, Daniel
Publicado no Sci Rep (2015)

A Rasch Analysis of the Charcot-Marie-Tooth Neuropathy Score (CMTNS) in a Cohort of Charcot-Marie-Tooth Type 1A Patients

Por Wang, Wenjia, Guedj, Mickaël, Bertrand, Viviane, Foucquier, Julie, Jouve, Elisabeth, Commenges, Daniel, Proust-Lima, Cécile, Murphy, Niall P., Blin, Olivier, Magy, Laurent, Cohen, Daniel, Attarian, Shahram
Publicado no PLoS One (2017)

Clinically Relevant Characterization of Lung Adenocarcinoma Subtypes Based on Cellular Pathways: An International Validation Study

Por Bryant, Christopher M., Albertus, Daniel L., Kim, Sinae, Chen, Guoan, Brambilla, Christian, Guedj, Mickael, Arima, Chinatsu, Travis, William D., Yatabe, Yasushi, Takahashi, Takashi, Brambilla, Elisabeth, Beer, David G.
Publicado em 2010

An array CGH based genomic instability index (G2I) is predictive of clinical outcome in breast cancer and reveals a subset of tumors without lymph node involvement but with poor pr...

Por Bonnet, Françoise, Guedj, Mickael, Jones, Natalie, Sfar, Sana, Brouste, Véronique, Elarouci, Nabila, Banneau, Guillaume, Orsetti, Béatrice, Primois, Charlotte, de Lara, Christine Tunon, Debled, Marc, de Mascarel, Isabelle, Theillet, Charles, Sévenet, Nicolas, de Reynies, Aurélien, MacGrogan, Gaëtan, Longy, Michel
Publicado em 2012

Combining two repurposed drugs as a promising approach for Alzheimer's disease therapy

Por Chumakov, Ilya, Nabirotchkin, Serguei, Cholet, Nathalie, Milet, Aude, Boucard, Aurélie, Toulorge, Damien, Pereira, Yannick, Graudens, Esther, Traoré, Sory, Foucquier, Julie, Guedj, Mickael, Vial, Emmanuel, Callizot, Noëlle, Steinschneider, Rémy, Maurice, Tangui, Bertrand, Viviane, Scart-Grès, Catherine, Hajj, Rodolphe, Cohen, Daniel
Publicado no Sci Rep (2015)

Molecular apocrine differentiation is a common feature of breast cancer in patients with germline PTEN mutations

Por Banneau, Guillaume, Guedj, Mickaël, MacGrogan, Gaëtan, de Mascarel, Isabelle, Velasco, Valerie, Schiappa, Renaud, Bonadona, Valerie, David, Albert, Dugast, Catherine, Gilbert-Dussardier, Brigitte, Ingster, Olivier, Vabres, Pierre, Caux, Frederic, de Reynies, Aurelien, Iggo, Richard, Sevenet, Nicolas, Bonnet, Françoise, Longy, Michel
Publicado em 2010

Polytherapy with a combination of three repurposed drugs (PXT3003) down-regulates Pmp22 over-expression and improves myelination, axonal and functional parameters in models of CMT1...

Por Chumakov, Ilya, Milet, Aude, Cholet, Nathalie, Primas, Gwenaël, Boucard, Aurélie, Pereira, Yannick, Graudens, Esther, Mandel, Jonas, Laffaire, Julien, Foucquier, Julie, Glibert, Fabrice, Bertrand, Viviane, Nave, Klaus-Armin, Sereda, Michael W, Vial, Emmanuel, Guedj, Mickaël, Hajj, Rodolphe, Nabirotchkin, Serguei, Cohen, Daniel
Publicado no Orphanet J Rare Dis (2014)

Association Study of ITGAM, ITGAX, and CD58 Autoimmune Risk Loci in Systemic Sclerosis: Results from 2 Large European Caucasian Cohorts

Por COUSTET, BAPTISTE, AGARWAL, SANDEEP K., GOURH, PRAVITT, GUEDJ, MICKAEL, MAYES, MAUREEN D., DIEUDE, PHILIPPE, WIPFF, JULIEN, AVOUAC, JEROME, HACHULLA, ERIC, DIOT, ELISABETH, CRACOWSKI, JEAN LUC, TIEV, KIET, SIBILIA, JEAN, MOUTHON, LUC, FRANCES, CAMILLE, AMOURA, ZAHIR, CARPENTIER, PATRICK, MEYER, OLIVIER, KAHAN, ANDRE, BOILEAU, CATHERINE, ARNETT, FRANK C., ALLANORE, YANNICK
Publicado em 2011

Independent Replication and Metaanalysis of Association Studies Establish TNFSF4 as a Susceptibility Gene Preferentially Associated with the Subset of Anticentromere-positive Patie...

Por COUSTET, BAPTISTE, BOUAZIZ, MATTHIEU, DIEUDÉ, PHILIPPE, GUEDJ, MICKAEL, BOSSINI-CASTILLO, LARA, AGARWAL, SANDEEP, RADSTAKE, TIMOTHY, MARTIN, JAVIER, GOURH, PRAVITT, ELHAI, MURIEL, KOUMAKIS, EUGÉNIE, AVOUAC, JÉRÔME, RUIZ, BARBARA, MAYES, MAUREEN, ARNETT, FRANK, HACHULLA, ERIC, DIOT, ELISABETH, CRACOWSKI, JEAN-LUC, TIEV, KIET, SIBILIA, JEAN, MOUTHON, LUC, FRANCES, CAMILLE, AMOURA, ZAHIR, CARPENTIER, PATRICK, COSNES, ANNE, MEYER, OLIVIER, KAHAN, ANDRÉ, BOILEAU, CATHERINE, CHIOCCHIA, GILLES, ALLANORE, YANNICK
Publicado em 2012

An exploratory randomised double-blind and placebo-controlled phase 2 study of a combination of baclofen, naltrexone and sorbitol (PXT3003) in patients with Charcot-Marie-Tooth dis...

Por Attarian, Shahram, Vallat, Jean-Michel, Magy, Laurent, Funalot, Benoît, Gonnaud, Pierre-Marie, Lacour, Arnaud, Péréon, Yann, Dubourg, Odile, Pouget, Jean, Micallef, Joëlle, Franques, Jérôme, Lefebvre, Marie-Noëlle, Ghorab, Karima, Al-Moussawi, Mahmoud, Tiffreau, Vincent, Preudhomme, Marguerite, Magot, Armelle, Leclair-Visonneau, Laurène, Stojkovic, Tanya, Bossi, Laura, Lehert, Philippe, Gilbert, Walter, Bertrand, Viviane, Mandel, Jonas, Milet, Aude, Hajj, Rodolphe, Boudiaf, Lamia, Scart-Grès, Catherine, Nabirotchkin, Serguei, Guedj, Mickael, Chumakov, Ilya, Cohen, Daniel
Publicado no Orphanet J Rare Dis (2014)