A Multi-Marker Genetic Association Test Based on the Rasch Model Applied to Alzheimer’s Disease

Results from Genome-Wide Association Studies (GWAS) have shown that the genetic basis of complex traits often include many genetic variants with small to moderate effects whose identification remains a challenging problem. In this context multi-marker analysis at the gene and pathway level can compl...

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Pubblicato in:PLoS One
Autori principali: Wang, Wenjia, Mandel, Jonas, Bouaziz, Jan, Commenges, Daniel, Nabirotchkine, Serguei, Chumakov, Ilya, Cohen, Daniel, Guedj, Mickaël
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574966/
https://ncbi.nlm.nih.gov/pubmed/26379234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138223
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