A Viral Discovery Methodology for Clinical Biopsy Samples Utilising Massively Parallel Next Generation Sequencing

Here we describe a virus discovery protocol for a range of different virus genera, that can be applied to biopsy-sized tissue samples. Our viral enrichment procedure, validated using canine and human liver samples, significantly improves viral read copy number and increases the length of viral conti...

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Detalhes bibliográficos
Main Authors: Daly, Gordon M., Bexfield, Nick, Heaney, Judith, Stubbs, Sam, Mayer, Antonia P., Palser, Anne, Kellam, Paul, Drou, Nizar, Caccamo, Mario, Tiley, Laurence, Alexander, Graeme J. M., Bernal, William, Heeney, Jonathan L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244418/
https://ncbi.nlm.nih.gov/pubmed/22216131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028879
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