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Distinct Toll-like Receptor Signals Regulate Cerebral Parasite Load and Interferon α/β and Tumor Necrosis Factor α–Dependent T-Cell Infiltration in the Brains of Trypanosoma brucei–Infected Mice
Background. The penetration of T cells and trypanosomes into the brain parenchyma is a major pathogenetic event in African trypanosomiasis. Methods. The role of innate immune responses in the penetration of T cells and Trypanosoma brucei brucei into the brain was studied in knockout mice by using do...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3244369/ https://ncbi.nlm.nih.gov/pubmed/22116836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir734 |
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