Distinct Toll-like Receptor Signals Regulate Cerebral Parasite Load and Interferon α/β and Tumor Necrosis Factor α–Dependent T-Cell Infiltration in the Brains of Trypanosoma brucei–Infected Mice

Background. The penetration of T cells and trypanosomes into the brain parenchyma is a major pathogenetic event in African trypanosomiasis. Methods. The role of innate immune responses in the penetration of T cells and Trypanosoma brucei brucei into the brain was studied in knockout mice by using do...

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Hlavní autoři: Amin, Daniel Ndem, Vodnala, Suman K., Masocha, Willias, Sun, Bo, Kristensson, Krister, Rottenberg, Martin E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
Major Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244369/
https://ncbi.nlm.nih.gov/pubmed/22116836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir734
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