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Minocycline Impedes African Trypanosome Invasion of the Brain in a Murine Model

Passage of Trypanosoma brucei across the blood-brain barrier (BBB) is a hallmark of late-stage human African trypanosomiasis. In the present study we found that daily administration of minocycline, a tetracycline antibiotic, impedes the penetration of leukocytes and trypanosomes into the brain paren...

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Detalhes bibliográficos
Main Authors: Masocha, Willias, Rottenberg, Martin E., Kristensson, Krister
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472198/
https://ncbi.nlm.nih.gov/pubmed/16641452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.5.1798-1804.2006
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