Specific Uptake of Tumor Necrosis Factor-α Is Involved in Growth Control of Trypanosoma brucei

Trypanosoma brucei is lysed by tumor necrosis factor-α (TNF-α) in a dose-dependent way, involving specific binding of the cytokine to a trypanosomal glycoprotein present in the flagellar pocket of the parasite. TNF-α–gold particles are endocytosed via coated pits and vesicles and are directed toward...

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Bibliographic Details
Main Authors: Magez, Stefan, Geuskens, Maurice, Beschin, Alain, del Favero, Herwig, Verschueren, Hendrik, Lucas, Ralf, Pays, Etienne, de Baetselier, Patrick
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1997
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2139880/
https://ncbi.nlm.nih.gov/pubmed/9151676
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