Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants

Memory B cells (MBCs) and long-lived plasma cells (LLPCs) persist after clearance of infection, yet the specific and nonredundant role MBCs play in subsequent protection is unclear. After resolution of West Nile virus infection in mice, we demonstrate that LLPCs were specific for a single dominant n...

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Hlavní autoři: Purtha, Whitney E., Tedder, Thomas F., Johnson, Syd, Bhattacharya, Deepta, Diamond, Michael S.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2011
Témata:
Brief Definitive Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244041/
https://ncbi.nlm.nih.gov/pubmed/22162833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110740
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