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Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells
Hematopoietic stem cell (HSC) populations change with aging, but the extent to which this is caused by qualitative versus quantitative alterations in HSC subtypes is unclear. Using clonal assays, in this study we show that the aging HSC compartment undergoes both quantitative and qualitative changes...
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| Главные авторы: | , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3244040/ https://ncbi.nlm.nih.gov/pubmed/22110168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111490 |
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