MiR-125a enhances self-renewal, lifespan, and migration of murine hematopoietic stem and progenitor cell clones

Expansion of hematopoietic stem cells (HSCs) is a ‘holy grail’ of regenerative medicine, as successful stem cell transplantations depend on the number and quality of infused HSCs. Although many attempts have been pursued to either chemically or genetically increase HSC numbers, neither clonal analys...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wojtowicz, Edyta Ewa, Broekhuis, Mathilde Johanna Christina, Weersing, Ellen, Dinitzen, Alexander, Verovskaya, Evgenia, Ausema, Albertina, Ritsema, Martha, Zwart, Erik, de Haan, Gerald, Bystrykh, Leonid V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423273/
https://ncbi.nlm.nih.gov/pubmed/30886165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-38503-z
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