Tracing Dynamics and Clonal Heterogeneity of Cbx7-Induced Leukemic Stem Cells by Cellular Barcoding

Accurate monitoring of tumor dynamics and leukemic stem cell (LSC) heterogeneity is important for the development of personalized cancer therapies. In this study, we experimentally induced distinct types of leukemia in mice by enforced expression of Cbx7. Simultaneous cellular barcoding allowed for...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Klauke, Karin, Broekhuis, Mathilde J.C., Weersing, Ellen, Dethmers-Ausema, Albertina, Ritsema, Martha, González, Marta Vilà, Zwart, Erik, Bystrykh, Leonid V., de Haan, Gerald
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297865/
https://ncbi.nlm.nih.gov/pubmed/25434821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.10.012
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