CEACAM1 dampens antitumor immunity by down-regulating NKG2D ligand expression on tumor cells

Although carcinoembryonic antigen (CEA)–related cell adhesion molecule 1 (CEACAM1) has been viewed as a tumor suppressor, increasing clinical evidence shows that high levels of CEACAM1 expression on tumors correlates with poor prognosis and high risk of metastasis. Here, we examined the consequences...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Chen, Zhangguo, Chen, Lanfen, Baker, Kristi, Olszak, Torsten, Zeissig, Sebastian, Huang, Yu-Hwa, Kuo, Timothy T., Mandelboim, Ofer, Beauchemin, Nicole, Lanier, Lewis L., Blumberg, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2011
Assuntos:
Brief Definitive Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244030/
https://ncbi.nlm.nih.gov/pubmed/22143889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20102575
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares