CEACAM1 dampens antitumor immunity by down-regulating NKG2D ligand expression on tumor cells

Although carcinoembryonic antigen (CEA)–related cell adhesion molecule 1 (CEACAM1) has been viewed as a tumor suppressor, increasing clinical evidence shows that high levels of CEACAM1 expression on tumors correlates with poor prognosis and high risk of metastasis. Here, we examined the consequences...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chen, Zhangguo, Chen, Lanfen, Baker, Kristi, Olszak, Torsten, Zeissig, Sebastian, Huang, Yu-Hwa, Kuo, Timothy T., Mandelboim, Ofer, Beauchemin, Nicole, Lanier, Lewis L., Blumberg, Richard S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2011
Gaiak:
Brief Definitive Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244030/
https://ncbi.nlm.nih.gov/pubmed/22143889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20102575
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