CEACAM1 dampens antitumor immunity by down-regulating NKG2D ligand expression on tumor cells

Although carcinoembryonic antigen (CEA)–related cell adhesion molecule 1 (CEACAM1) has been viewed as a tumor suppressor, increasing clinical evidence shows that high levels of CEACAM1 expression on tumors correlates with poor prognosis and high risk of metastasis. Here, we examined the consequences...

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Bibliografiska uppgifter
Huvudupphovsmän: Chen, Zhangguo, Chen, Lanfen, Baker, Kristi, Olszak, Torsten, Zeissig, Sebastian, Huang, Yu-Hwa, Kuo, Timothy T., Mandelboim, Ofer, Beauchemin, Nicole, Lanier, Lewis L., Blumberg, Richard S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2011
Ämnen:
Brief Definitive Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244030/
https://ncbi.nlm.nih.gov/pubmed/22143889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20102575
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