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Lack of germline PALB2 mutations in melanoma-prone families with CDKN2A mutations and pancreatic cancer

The presence of pancreatic cancer (PC) in melanoma-prone families has been consistently associated with an increased frequency of CDKN2A mutations, the major high-risk susceptibility gene identified for melanoma. However, the precise relationship between CDKN2A, melanoma and PC remains unknown. We e...

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Autori principali: Yang, Xiaohong R, Jessop, Lea, Myers, Timothy, Amundadottir, Laufey, Pfeiffer, Ruth M., Wheeler, William, Pike, Kristen M., Yuenger, Jeff, Burdett, Laurie, Yeager, Meredith, Chanock, Stephen J., Tucker, Margaret A., Goldstein, Alisa M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244023/
https://ncbi.nlm.nih.gov/pubmed/21614589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-011-9447-9
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