Immortalization of mouse myogenic cells can occur without loss of p16(INK4a), p19(ARF), or p53 and is accelerated by inactivation of Bax

BACKGROUND: Upon serial passaging of mouse skeletal muscle cells, a small number of cells will spontaneously develop the ability to proliferate indefinitely while retaining the ability to differentiate into multinucleate myotubes. Possible gene changes that could underlie myogenic cell immortalizati...

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Detalhes bibliográficos
Main Authors: Nowak, Jonathan A, Malowitz, Jonathan, Girgenrath, Mahasweta, Kostek, Christine A, Kravetz, Amanda J, Dominov, Janice A, Miller, Jeffrey Boone
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC324393/
https://ncbi.nlm.nih.gov/pubmed/14711384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-5-1
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