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Inhibition of Eco RI action by polynucleotides. A characterization of the non-specific binding of the enzyme to DNA.

The cleavage of the plasmid pBR322 by the restriction endonuclease Eco RI has been studied in the presence of various polynucleotides and the double stranded octanucleotide d-(GGAATTCC) in order to clarify whether there is a preferential interaction of Eco RI with DNA sequences other than -GAATTC-....

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Bibliographic Details
Main Authors: Langowski, J, Pingoud, A, Goppelt, M, Maass, G
Format: Artigo
Language:Inglês
Published: 1980
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC324382/
https://ncbi.nlm.nih.gov/pubmed/6255431
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