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Sox2 maintains self-renewal of tumor initiating cells in osteosarcomas
Tumors are thought to be sustained by a reservoir of self-renewing cells, termed tumor initiating cells or cancer stem cells. Osteosarcomas are high-grade sarcomas derived from osteoblast progenitor cells and are the most common pediatric bone malignancy. In this report we show that the stem cell tr...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3243769/ https://ncbi.nlm.nih.gov/pubmed/21927024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.405 |
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